N6-CYCLOHEXYLADENOSINE
- Product Name
- N6-CYCLOHEXYLADENOSINE
- CAS No.
- 36396-99-3
- Chemical Name
- N6-CYCLOHEXYLADENOSINE
- Synonyms
- CHA;Cyclohexyladenosine;N-Cyclohexyladenosine;N6-CYCLOHEXYLADENOSINE;Adenosine, N-cyclohexyl-;N6-Cyclohexyladenosine,CHA;N(sup 6)-cyclohexyladenosine;(2R,4S)-4-fluoropyrrolidine-6-carboxylicacid;N6-CYCLOHEXYLADENOSINE (CHA) SELECTIVE A 1 ADENOSIN;(2R,3R,4S,5R)-2-(6-(CyclohexylaMino)-9H-purin-9-yl)-5-(hydroxyMethyl)tetrahydrofuran-3,4-diol
- CBNumber
- CB4468462
- Molecular Formula
- C16H23N5O4
- Formula Weight
- 349.38
- MOL File
- 36396-99-3.mol
N6-CYCLOHEXYLADENOSINE Property
- Melting point:
- 182 - 184°C
- Boiling point:
- 675.2±65.0 °C(Predicted)
- Density
- 1.71±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 13.12±0.70(Predicted)
- color
- White to Off-White
- Stability:
- Hygroscopic
Safety
- WGK Germany
- 3
- HS Code
- 29349990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 28427
- Product name
- N6-Cyclohexyladenosine
- Packaging
- 50mg
- Price
- $96
- Updated
- 2024/03/01
- Product number
- 28427
- Product name
- N6-Cyclohexyladenosine
- Packaging
- 100mg
- Price
- $180
- Updated
- 2024/03/01
- Product number
- 28427
- Product name
- N6-Cyclohexyladenosine
- Packaging
- 25mg
- Price
- $62
- Updated
- 2024/03/01
- Product number
- 6863
- Product name
- N6-Cyclohexyladenosine
- Purity
- ≥98%(HPLC)
- Packaging
- 50
- Price
- $85
- Updated
- 2021/12/16
- Product number
- C989785
- Product name
- N6-Cyclohexyladenosine
- Packaging
- 500mg
- Price
- $745
- Updated
- 2021/12/16
N6-CYCLOHEXYLADENOSINE Chemical Properties,Usage,Production
Description
N6-Cyclohexyladenosine is an adenosine receptor agonist. It selectively binds to adenosine A1 receptors in rat cortical membranes (IC50 = 2.3 nM) over A2 receptors in rat striatal membranes (IC50 = 870 nM). N6-Cyclohexyladenosine decreases heart rate and increases coronary flow in a perfused working rat heart model ex vivo (EC25s = 5 and 860 nM, respectively). In vivo, it decreases heart rate and blood pressure in normotensive rats (EC25s = 2.4 and 4.2 μg/kg, respectively). N6-Cyclohexyladenosine (100 μM) induces sleep in rats when administered via basal forebrain infusion. N6-Cyclohexyladenosine also decreases locomotor activity in mice (ED50 = 60 μg/kg, i.p.).
Uses
N6-Cyclohexyladenosine is a derivative of Adenosine (A280400), and is used testing adenosine A1 and A2A receptor activation for pharmaceuticals such as antidepressants. N6-Cyclohexyladenosine also is used as a JAK2 inhibitor, blocking STAT3 signalling in human cancer cells.
Biochem/physiol Actions
Selective A1 adenosine receptor agonist.
storage
Store at -20°C
N6-CYCLOHEXYLADENOSINE Preparation Products And Raw materials
Raw materials
Preparation Products
N6-CYCLOHEXYLADENOSINE Suppliers
- Tel
- 021-58955995
- Fax
- 609-228-5909
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- Country
- United States
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- +1-800-259-7612
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- +1-800-259-7612
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- United States
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- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com
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- United States
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- +1-833-552-7181
- sales@aladdinsci.com
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- United States
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